Nur77 Mouse anti-Mouse, PE, Clone: 12.14, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5965-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15208949

Quantity Price
1 £ 161.27 / 100µg
EU Stock 12
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Description and Specification

Specification

Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Concentration 0.2mg/mL
Gene Alias NGFI-B, NR4A1, TR3, NAK1
Clone 12.14
Format Conjugated
Applications Flow Cytometry (Intracellular Staining)
Conjugate PE
Isotype IgG1
Antigen Nur77
Host Species Mouse
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg

This 12.14 monoclonal antibody reacts with mouse Nur77 (also known as NR4A1, TR3, NGFI-B, or NAK1), an inducible orphan nuclear receptor. Expressed in thymocytes and T cell lines, Nur77 promotes apoptosis and plays a role in thymocyte negative selection. Additionally, Nur77 has been shown to be critical for steroid biosynthesis in Leydig cells as well as for the effects of dopamine. In addition, Nur77 has been shown to interact with FoxP3 in regulatory T cells. However, our results with this antibody do not correlate with this observation.