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Tocris Bioscience™ NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic

Brand:  Tocris Bioscience™ 2161/10

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13460694

  • £157.29 / 10mg

Estimated Shipment date
from Supplier 03-04-2020

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Description

Description

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ∽ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotypes in prostate cancer cells.
Specifications

Specifications

NSC 23766
>96
10mg
Rho GTPase Inhibitors
530.97
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