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Tocris Bioscience™ NSC 146109 hydrochloride

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

POA

Specifications

Purity >99%
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Description

Description

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.
Specifications

Specifications

>99%
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