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Tocris Bioscience™ NSC 146109 hydrochloride
Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription
POA
Description
Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.Specifications
>99% |
For Research Use Only