Tocris Bioscience™ NS 398

Cyclooxygenase-2 (COX-2) inhibitor

Description

Selective cyclooxygenase-2 inhibitor (IC50 values are 3.8 and > 100 μM for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro. Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo.

Specifications

• Chemical Name or Material: N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide
• Assay Percent Range: >99%
• Molecular Formula: C₁₃H₁₈N₂O₅S

• CAS: 123653-11-2
• Solubility: Soluble to 100mM in DMSO
• Formula Weight: Observed MW: 314.36

For Research Use Only