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NS 3623, Tocris Bioscience™

KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic

Brand:  RD Systems (Bio-Techne) 4462/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464794

  • £183.48 / 10mg


Estimated Shipment
29-10-2018
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Description

Description

KV11.1 (hERG) and KV4.3 channel activator. Activates the IKr and Ito currents and displays antiarrhythmic activity. May also act as a partial blocker of KV11.1 channels. Displays selectivity over the key cardiac potassium channels, KV7.1 (KCNQ1) and KV1.5. Suitable for both in vitro and in vivo use.
Specifications

Chemical Identifiers

343630-41-1
427.185
d0jy2k, 1-4-bromo-2-2h-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea, i kr agonists arrhythmia , neurosearch, herg potassium channel openers arrhythmia, herg potassium channel openers arrhythmia , neurosearch, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3'-trifluoromethylphenyl urea, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3-trifluoromethyl phenyl-urea, rapid delayed-rectifier current activators acquired long qt syndrome , neruosearch, 1-4-bromo-2-1h-1,2,3,4-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea
1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
C15H10BrF3N6O
JXPULDIATMTIIN-UHFFFAOYSA-N
9954236
C1=CC(=CC(=C1)NC(=O)NC2=C(C=C(C=C2)Br)C3=NNN=N3)C(F)(F)F

Specifications

NS 3623
343630-41-1
d0jy2k, 1-4-bromo-2-2h-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea, i kr agonists arrhythmia , neurosearch, herg potassium channel openers arrhythmia, herg potassium channel openers arrhythmia , neurosearch, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3'-trifluoromethylphenyl urea, n-4-bromo-2-1h-tetrazol-5-yl-phenyl-n'-3-trifluoromethyl phenyl-urea, rapid delayed-rectifier current activators acquired long qt syndrome , neruosearch, 1-4-bromo-2-1h-1,2,3,4-tetrazol-5-yl phenyl-3-3-trifluoromethyl phenyl urea
C1=CC(=CC(=C1)NC(=O)NC2=C(C=C(C=C2)Br)C3=NNN=N3)C(F)(F)F
427.185
427.18
10mg
C15H10BrF3N6O
JXPULDIATMTIIN-UHFFFAOYSA-N
1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
9954236
>99%
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