NOS2 Rat anti-Mouse, Clone: CXNFT, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5920-80

UNSPSC: 12352200

Code: NEW

Additional Details:
Additional Details: Weight: 0.50000kg



Disclaimers: For Research Use Only.

Product Code. 15285053

Quantity Price
1 £ 60.53 / Each
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Conjugate Unlabeled
Applications Flow Cytometry (Intracellular Staining)
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Antigen NOS2
Quantity 25μg
Regulatory Status RUO
Clone CXNFT
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Isotype IgG2a
Gene Alias iNOS, nitric oxide synthase 2
Format Purified
Species Reactivity Mouse

This CXNFT monoclonal antibody reacts to mouse NOS2 (inducible NOS, iNOS). Nitric oxide synthase enzymes catalyze the formation of nitric oxide from L-arginine through an NADPH- and oxygen-dependent mechanism. There are three isoforms of NOS that are encoded by three separate genes. NOS1 (neuronal NOS, nNOS) and NOS3 (endothelial NOS, eNOS) are constitutively expressed, while NOS2 is induced in response to bacterial endotoxins and inflammatory cytokines such as IFN gamma and TNF alpha. NOS2 is expressed by myeloid-derived suppressor cells and M1 macrophages but not alternatively activated M2 macrophages. NOS enzymes are functionally active only when they form homodimers, and dimerization of NOS2 occurs at steady-state concentrations of free Ca2+ such that NOS2 is functionally active when it is produced.