missing translation for 'onlineSavingsMsg'
Learn More

NNC 05-2090 hydrochloride, Tocris Bioscience™

GABA uptake inhibitor; moderately BGT-1 selective

Brand:  Tocris (Bio-Techne) 274710

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13440514

  • £183.48 / 10mg

Estimated Shipment date
from Supplier 01-10-2019

Please to purchase this item. Need a web account? Register with us today!


Description

Description

GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α1- and D2-receptors (IC50 values are 266 and 1632 nM respectively).
Specifications

Chemical Identifiers

184845-18-9
451.007
nnc 05-2090 hydrochloride, 1-3-9h-carbazol-9-yl propyl-4-2-methoxyphenyl-4-piperidinol hydrochloride, 1-3-9h-carbazol-9-yl-1-propyl-4-2-methoxyphenyl piperidin-4-ol hydrochloride, 1-3-9h-carbazol-9-yl propyl-4-2-methoxyphenyl piperidin-4-ol-hydrogen chloride 1/1
1-(3-carbazol-9-ylpropyl)-4-(2-methoxyphenyl)piperidin-4-ol;hydrochloride
C27H31ClN2O2
WDFXPKKFSNMGOO-UHFFFAOYSA-N
18782760
COC1=CC=CC=C1C2(CCN(CC2)CCCN3C4=CC=CC=C4C5=CC=CC=C53)O.Cl

Specifications

NNC 05-2090 hydrochloride
184845-18-9
nnc 05-2090 hydrochloride, 1-3-9h-carbazol-9-yl propyl-4-2-methoxyphenyl-4-piperidinol hydrochloride, 1-3-9h-carbazol-9-yl-1-propyl-4-2-methoxyphenyl piperidin-4-ol hydrochloride, 1-3-9h-carbazol-9-yl propyl-4-2-methoxyphenyl piperidin-4-ol-hydrogen chloride 1/1
COC1=CC=CC=C1C2(CCN(CC2)CCCN3C4=CC=CC=C4C5=CC=CC=C53)O.Cl
451.007
451.01
10mg
C27H31ClN2O2
WDFXPKKFSNMGOO-UHFFFAOYSA-N
1-(3-carbazol-9-ylpropyl)-4-(2-methoxyphenyl)piperidin-4-ol;hydrochloride
18782760
>98%
Videos
Documents