missing translation for 'onlineSavingsMsg'
Learn More

NH 125, Tocris Bioscience™

CaM kinase III (eEF-2 kinase) inhibitor

Brand:  Tocris (Bio-Techne) 343950

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13433024

  • £710.01 / 50mg

Estimated Shipment date
from Supplier 26-03-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Decreases the viability of a variety of cancer cell lines (IC50 values are 0.7 - 4.8 μM) and blocks G1/S cell cycle progression. Shown to induce eEF-2 phosphorylation in cancer cells. Also an effective antibacterial agent; inhibits histidine protein kinase in vitro (IC50 = 6.6 μM) and in vivo.
Specifications

Chemical Identifiers

278603-08-0
524.575
1-benzyl-3-cetyl-2-methylimidazolium iodide, eef-2 kinase inhibitor, nh125, 1-hexadecyl-2-methyl-3-phenylmethyl-1h-imidazolium iodide, nh hplc , solid, 1-benzyl-3-hexadecyl-2-methylimidazol-1-ium iodide
1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide
C27H45IN2
RVWOHCBHAGBLLT-UHFFFAOYSA-M
10436839
CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-]

Specifications

NH 125
278603-08-0
1-benzyl-3-cetyl-2-methylimidazolium iodide, eef-2 kinase inhibitor, nh125, 1-hexadecyl-2-methyl-3-phenylmethyl-1h-imidazolium iodide, nh hplc , solid, 1-benzyl-3-hexadecyl-2-methylimidazol-1-ium iodide
CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-]
524.575
524.56
50mg
C27H45IN2
RVWOHCBHAGBLLT-UHFFFAOYSA-M
1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide
10436839
>98%
Videos
Documents