NGFR Mouse, PE, Clone: ME20.4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9400-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15517206

Quantity Price
1 £ 78.59 / 25 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Isotype IgG1
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Host Species Mouse
Quantity 25 tests
Applications Flow Cytometry
Applications Microscopy
Applications Western Blotting
Species Reactivity Canine, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Sheep
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test
Conjugate PE
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen NGFR
Regulatory Status RUO
Primary or Secondary Primary
Clone ME20.4

The monoclonal antibody ME20.4 recognizes CD271, a 75 kDa, type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9.

The ME20.4 monoclonal antibody recognizes human, non-human primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.