NGFR Mouse, Clone: ME20.4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9400-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15537596

Quantity Price
1 £ 61.7 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Format Purified
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Microscopy
Applications Western Blotting
Clone ME20.4
Host Species Mouse
Conjugate Unlabeled
Concentration 0.5mg/mL
Regulatory Status RUO
Antigen NGFR
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Canine, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Sheep
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Quantity 25μg

The monoclonal antibody ME20.4 recognizes CD271, a 75kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9.

The ME20.4 monoclonal antibody recognizes human, non-human primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.