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NGFR Mouse, Clone: ME20.4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9400-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15537596

  • £61.70 / 25µg


Estimated Shipment date
from Supplier 27-11-2017
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody ME20.4 recognizes CD271, a 75kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9.

The ME20.4 monoclonal antibody recognizes human, non-human primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.
Specifications

Specifications

NGFR
ME20.4
Unlabeled
Purified
IgG1
RUO
Primary
Sheep
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C.
Monoclonal