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NF 157, Tocris Bioscience™

Selective P2Y11/P2X1 antagonist

Brand:  Tocris (Bio-Techne) 2450/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13441234

  • £149.85 / 10mg

Estimated Shipment
28-06-2019

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Description

Description

Purinergic receptor antagonist that potently inhibits P2Y11 receptor activity (IC50 = 463 nM). Displays selectivity for P2Y11 and P2X1 receptors over P2Y1, P2Y2, P2X2, P2X3, P2X4 and P2X7 receptors. Inhibits NAD+-induced activation of human granulocytes.
Specifications

Chemical Identifiers

104869-26-3
1437.077
8,8'-carbonylbis imino-3,1-phenylenecarbonylimino 4-fluoro-3,1-phenylene carbonylimino bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(8-oxidoperoxysulfanyl-4,6-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
C49H28F2N6Na6O23S6
QJFCMJZVZFAWGF-UHFFFAOYSA-H
71433548
C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])SOO[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Specifications

NF 157
104869-26-3
8,8'-carbonylbis imino-3,1-phenylenecarbonylimino 4-fluoro-3,1-phenylene carbonylimino bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])SOO[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
1437.077
1437.08
10mg
C49H28F2N6Na6O23S6
QJFCMJZVZFAWGF-UHFFFAOYSA-H
hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(8-oxidoperoxysulfanyl-4,6-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate
71433548
>98%
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