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Neural / Glial Antigen 2 (NG2) Mouse anti-Human, Clone: 9.2.27, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6504-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15267717

  • £127.80 / 100µg


Estimated Shipment
07-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 9.2.27 monoclonal antibody reacts with human neural/glial antigen 2, which is also known as melanoma chondroitin sulfate proteoglycan (MCSP). This antigen is composed of a 250kDa N-linked glycoprotein and a >450kDa proteoglycan. NG2 is present on the surface of >90% of malignant melanomas in addition to some non-melanomic tumors. Moreover, NG2 is expressed on glioma cells, as well as on developing and adult oligodendrocyte precursor cells. Studies have demonstrated the involvement of this protein in tumor cell proliferation, adhesion, migration, and invasion. NG2 also functions as a coreceptor for alpha4beta1 integrin. Finally, expression of NG2 can be used as a prognostic marker for disorders such as acral letiginous melanoma and infantile acute myeloid leukemia.

The 9.2.27 antibody has been reported to suppress melanoma tumor growth.
Description & Specifications

Specifications

Neural / Glial Antigen 2 (NG2)
9.2.27
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C.
Monoclonal
Immunoprecipitation
0.5mg/mL
Purified
Chondroitin Sulfate Proteoglycan, MCSP/melanoma chondroitin sulfate proteoglycan
IgG2a
RUO
Primary
Human