Nestin Mouse anti-Human, eFluor 570, Clone: 10C2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 41-9843-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15508986

Quantity Price
1 £ 86.73 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
Add to basket


Description and Specification

Specification

Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Quantity 25μg
Species Reactivity Human
Primary or Secondary Primary
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Isotype IgG1
Antigen Nestin
Clone 10C2
Host Species Mouse
Concentration 0.2mg/mL
Conjugate eFluor 570
Regulatory Status RUO

The monoclonal antibody 10C2 recognizes human nestin (residues 1464-1614). Nestin is a 220-240kDa Class VI intermediate filament protein that is expressed in stem cells of the developing nervous system. Expression has also been found in pancreatic islet and mesenchymal precursors in addition to cells with angiogenic potential. Upon differentiation, nestin-containing filaments are replaced by cell type-specific intermediate filament proteins, such as GFAP. Expression has been identified in a variety of cancerous cells including glioblastomas and pancreatic tumors. No cross-reactivity to rodent nestins has been observed using the 10C2 antibody.