Nestin Mouse anti-Human, Alexa Fluor 488, Clone: 10C2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9843-80

25UG ANTI-HUMAN NESTIN ALEXA FLUOR® 488

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15302090

Quantity Price
1 £ 86.73 / 25µg
Estimated Shipment date
from Supplier 28-03-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Microscopy
Isotype IgG1
Quantity 25μg
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 10C2
Antigen Nestin
Format Conjugated
Regulatory Status RUO
Species Reactivity Human
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Conjugate Alexa Fluor 488

The monoclonal antibody 10C2 recognizes human nestin (residues 1464-1614). Nestin is a 220-240kDa Class VI intermediate filament protein that is expressed in stem cells of the developing nervous system. Expression has also been found in pancreatic islet and mesenchymal precursors in addition to cells with angiogenic potential. Upon differentiation, nestin-containing filaments are replaced by cell type-specific intermediate filament proteins, such as GFAP. Expression has been identified in a variety of cancerous cells including glioblastomas and pancreatic tumors. No cross-reactivity to rodent nestins has been observed using the 10C2 antibody.