Nemonapride, Tocris Bioscience™

Highly potent D2-like antagonist. Also 5-HT1A agonist

Brand:  Tocris (Bio-Techne) 174650

Product Code. 13458693

Description

Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.

Chemical Identifiers

• Chemical Name or Material: Nemonapride
• Molecular Formula: C21H26ClN3O2
• Synonym: cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide

Specifications

• Chemical Name or Material: Nemonapride
• CAS: 75272-39-8
• Molecular Formula: C21H26ClN3O2
• Synonym: cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide
• SMILES: CC1C(CCN1CC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3OC)NC)Cl
• PubChem CID: 9952220

• Formula Weight: 387.91
• Purity Grade: >99%
• Quantity: 50mg
• InChI Key: KRVOJOCLBAAKSJ-KSSFIOAISA-N
• Molecular Weight (g/mol): 387.908
• ChEBI: CHEBI:64218