Nemonapride, Tocris Bioscience™

Highly potent D2-like antagonist. Also 5-HT1A agonist

Brand:  Tocris (Bio-Techne) 174650

Product Code. 13458693

Description

Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.

Chemical Identifiers

• CAS: 75272-39-8
• Molecular Weight (g/mol): 387.908
• Synonym: nemonapride, --nemonapride, 2s,3s-nemonapride, emonapride, emilace, n-2s,3s-1-benzyl-2-methylpyrrolidin-3-yl-5-chloro-2-methoxy-4-methylamino benzamide, dsstox_cid_22612, dsstox_rid_80057, dsstox_gsid_42612, cis-n-1-benzyl-2-methylpyrrolidin-3-yl-5-chloro-2-methoxy-4-methylaminobenzamide
• ChEBI: CHEBI:64218
• SMILES: CC1C(CCN1CC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3OC)NC)Cl

• Molecular Formula: C21H26ClN3O2
• InChI Key: KRVOJOCLBAAKSJ-KSSFIOAISA-N
• PubChem CID: 9952220
• IUPAC Name: N-[(2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide

Specifications

• Chemical Name or Material: Nemonapride
• CAS: 75272-39-8
• Synonym: nemonapride, --nemonapride, 2s,3s-nemonapride, emonapride, emilace, n-2s,3s-1-benzyl-2-methylpyrrolidin-3-yl-5-chloro-2-methoxy-4-methylamino benzamide, dsstox_cid_22612, dsstox_rid_80057, dsstox_gsid_42612, cis-n-1-benzyl-2-methylpyrrolidin-3-yl-5-chloro-2-methoxy-4-methylaminobenzamide
• SMILES: CC1C(CCN1CC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3OC)NC)Cl
• Molecular Weight (g/mol): 387.908
• ChEBI: CHEBI:64218
• Percent Purity: >99%

• Quantity: 50mg
• Molecular Formula: C21H26ClN3O2
• InChI Key: KRVOJOCLBAAKSJ-KSSFIOAISA-N
• IUPAC Name: N-[(2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
• PubChem CID: 9952220
• Formula Weight: 387.91