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NCX 4040, Tocris Bioscience™

NO-donating aspirin; anti-inflammatory and antitumor

Brand:  RD Systems (Bio-Techne) 4531/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464894

  • £151.80 / 10mg


Estimated Shipment
08-01-2019
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Description

Description

NO-donating aspirin; anti-inflammatory. Blocks inflammatory mediator production in isolated human monocytes (IC50 values are 0.07, 0.13, 0.15 and 0.18μM for IL-1β, PGE2, IL-10 and TNF-α respectively). Decreases COX-2 expression (IC50 = 0.13μM); disrupts proteasome-mediated degradation of iκB-α. Antiproliferative in HCT116 colon cancer cells; sensitizes drug-resistant ovarian tumor cells to cisplatin (Cat. No. 2251).
Specifications

Chemical Identifiers

287118-97-2
331.28
no-aspirin, 2-acetyloxy benzoic acid 4-nitrooxy methyl phenyl ester, 2-acetyloxy-4-nitrooxy methyl phenyl ester, benzoic acid, 4-nitrooxy methyl phenyl 2-acetyloxy benzoate, 4-nitrooxymethyl phenyl 2-acetoxybenzoate, ncx hplc, 2-acetyloxy benzoic acid 4-nitroxymethyl phenyl ester, 2-acetyloxy benzoic acid 4-nitrooxymethyl phenylester
[4-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate
C16H13NO7
CTHNKWFUDCMLIQ-UHFFFAOYSA-N
9818919
CC(=O)OC1=CC=CC=C1C(=O)OC2=CC=C(C=C2)CO[N+](=O)[O-]

Specifications

NCX 4040
287118-97-2
no-aspirin, 2-acetyloxy benzoic acid 4-nitrooxy methyl phenyl ester, 2-acetyloxy-4-nitrooxy methyl phenyl ester, benzoic acid, 4-nitrooxy methyl phenyl 2-acetyloxy benzoate, 4-nitrooxymethyl phenyl 2-acetoxybenzoate, ncx hplc, 2-acetyloxy benzoic acid 4-nitroxymethyl phenyl ester, 2-acetyloxy benzoic acid 4-nitrooxymethyl phenylester
CC(=O)OC1=CC=CC=C1C(=O)OC2=CC=C(C=C2)CO[N+](=O)[O-]
331.28
331.28
10mg
C16H13NO7
CTHNKWFUDCMLIQ-UHFFFAOYSA-N
[4-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate
9818919
>98%
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