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Tocris Bioscience™ NBQX disodium salt
Potent AMPA antagonist; more water soluble form of NBQX (Cat. No. 0373)
POA
Specifications
| Chemical Name or Material | 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt |
|---|---|
| CAS | 479347-86-9 |
| Assay Percent Range | >98% |
| Solubility | Soluble to 100mM in water |
| Molecular Formula | C12H6N4O6SNa2 |
Description
NBQX disodium salt is a selective and competitive AMPA and kainate receptor antagonist (IC50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo.NBQX disodium salt is a more water-soluble form of NBQX (Cat. No. 0373).
Specifications
| 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt | |
| >98% | |
| C12H6N4O6SNa2 |
| 479347-86-9 | |
| Soluble to 100mM in water | |
| Observed MW: 380.24 |
For Research Use Only