missing translation for 'onlineSavingsMsg'
Learn More

NAS-181, Tocris Bioscience™

Selective r5-HT1B antagonist; active in vivo

Brand:  Tocris (Bio-Techne) 141310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13439463

  • £227.85 / 10mg

Call for latest availability
+44 (0)1509 555 500

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Potent, selective antagonist at the rat 5-HT1B receptor (Ki = 47 nM). Increases synthesis and metabolism of 5-HT in the brain following systemic administration and improves passive avoidance retention performance in vivo. Increases subthalamic nucleus-triggered complex EPSCs and burst firing in SNr GABA neurons
Specifications

Chemical Identifiers

1217474-40-2
538.627
2r-2-3-4-morpholinylmethyl-2h-1-benzopyran-8-yl oxy methyl morpholine dimethanesulfonate, 2r-2-3-morpholin-4-ylmethyl-2h-chromen-8-yl oxy methyl morpholine; bis methanesulfonic acid, methanesulfonic acid-2r-2-3-morpholin-4-yl methyl-2h-1-benzopyran-8-yl oxy methyl morpholine 2/1
methanesulfonic acid;(2R)-2-[[3-(morpholin-4-ylmethyl)-2H-chromen-8-yl]oxymethyl]morpholine
C21H34N2O10S2
WMRMIRRDPBKNMY-ZEECNFPPSA-N
45073445
CS(=O)(=O)O.CS(=O)(=O)O.C1COC(CN1)COC2=CC=CC3=C2OCC(=C3)CN4CCOCC4

Specifications

10mg
1217474-40-2
2r-2-3-4-morpholinylmethyl-2h-1-benzopyran-8-yl oxy methyl morpholine dimethanesulfonate, 2r-2-3-morpholin-4-ylmethyl-2h-chromen-8-yl oxy methyl morpholine; bis methanesulfonic acid, methanesulfonic acid-2r-2-3-morpholin-4-yl methyl-2h-1-benzopyran-8-yl oxy methyl morpholine 2/1
CS(=O)(=O)O.CS(=O)(=O)O.C1COC(CN1)COC2=CC=CC3=C2OCC(=C3)CN4CCOCC4
538.627
538.63
NAS-181
C21H34N2O10S2
WMRMIRRDPBKNMY-ZEECNFPPSA-N
methanesulfonic acid;(2R)-2-[[3-(morpholin-4-ylmethyl)-2H-chromen-8-yl]oxymethyl]morpholine
45073445
>97%
Videos
Documents