missing translation for 'onlineSavingsMsg'
Learn More

Nanog Mouse anti-Human, Clone: hNanog.2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5768-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15217457

  • £78.88 / 25µg


Estimated Shipment
02-11-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The hNanog.2 antibody recognizes human Nanog, a homeobox transcription factor expressed in embryonic stem cells (ESC). Nanog is essential for self-renewal of ESC and the inner cell mass and is throught to function in the same capacity as other factors such as Oct4 and Sox2. Nanog plays a crucial role in embryonic cell fate specification following formation of the blastocyst by regulating proliferation and preventing differentiation. Nanog functions by directly binding DNA consensus sequences to activate or repress transcription. In differentiating ESC, Nanog binds to its own promoter leading to repression of expression. Nanog has been reported to be overexpressed in germ cell tumors of the gonads and central nervous system as well as breast and colorectal cancer.
Specifications

Specifications

Nanog
hNanog.2
Unlabeled
Purified
IgG1
RUO
Primary
Human
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C.
Monoclonal