missing translation for 'onlineSavingsMsg'
Learn More

Naloxone benzoylhydrazone, Tocris Bioscience™

Full κ agonist, partial μ and δ agonist and antagonizes agonist-induced activation of NOP. Restrictions apply. See special conditions on product page.

Brand:  Tocris (Bio-Techne) 141910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13439473

  • £91.80 / 10mg

Estimated Shipment
28-06-2019

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Mixed opioid receptor agonist/antagonist. Acts as a potent and full agonist at κ, a partial agonist atμ and δ opioid receptors (pEC50 values are 9.45, 8.74 and 8.61 in a cAMP assay, 9.70, 8.59 and 8.49 in a [35S]GTPγS binding assay respectively). Fails to exert agonist effects at NOP receptors and antagonizes agonist-induced NOP activation. Stimulates κ-,μ- and δ-mediated analgesia and blocks NOP-induced supraspinal nociception.
Specifications

Chemical Identifiers

119630-94-3
445.519
naloxone benzoylhydrazone, a-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide benzoic acid, nalbzoh, 6-desoxy-6-benzoylhydrazido-n-allyl-14-hydroxydihydronormorphinone, benzoic acid, 5alpha-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide, d05zyz, 5alpha-4,5-epoxy, naloxone benzoylhydrazone, solid, 3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide benzoic acid, 5?-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene benzoic acid hydrazide, 5
N-[(E)-[(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene]amino]benzamide
C26H27N3O4
AKXCFAYOTIEFOH-XTNAHFASSA-N
9601084
C=CCN1CCC23C4C(=NNC(=O)C5=CC=CC=C5)CCC2(C1CC6=C3C(=C(C=C6)O)O4)O

Specifications

Naloxone benzoylhydrazone
119630-94-3
naloxone benzoylhydrazone, a-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide benzoic acid, nalbzoh, 6-desoxy-6-benzoylhydrazido-n-allyl-14-hydroxydihydronormorphinone, benzoic acid, 5alpha-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide, d05zyz, 5alpha-4,5-epoxy, naloxone benzoylhydrazone, solid, 3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene hydrazide benzoic acid, 5?-4,5-epoxy-3,14-dihydroxy-17-2-propenyl morphinan-6-ylidene benzoic acid hydrazide, 5
C=CCN1CCC23C4C(=NNC(=O)C5=CC=CC=C5)CCC2(C1CC6=C3C(=C(C=C6)O)O4)O
445.519
445.52
10mg
C26H27N3O4
AKXCFAYOTIEFOH-XTNAHFASSA-N
N-[(E)-[(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ylidene]amino]benzamide
9601084
>99%
Videos