Myosin Mouse, Alexa Fluor 488, Clone: SMMS-1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-6400-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15520237

Quantity Price
1 £ 174.09 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Species Reactivity Bovine, Canine, cat, Rat
Clone SMMS-1
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Regulatory Status RUO
Host Species Mouse
Antigen Myosin
Concentration 0.5mg/mL
Gene Alias smooth muscle myosin heavy chains, SM1 and SM2 isoforms
Primary or Secondary Primary
Conjugate Alexa Fluor 488
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This SMMS-1 monoclonal antibody reacts with both isoforms of the human smooth muscle myosin heavy chain (SM1 and SM2) structural proteins, which are components of the contractile apparatus in smooth muscle cells. Smooth muscle myosin heavy chains are expressed by myoepithelial cells and also serve as the terminal differentiation marker for smooth muscle cells. In normal breast tissue, myoepithelial cells compose the outer layer of the lumen lining. In benign and in situ breast lesions, the intact myoepithelial layer stains with SMMS-1 and the loss of this staining indicates invasive cancer. This SMMS-1 antibody has also been reported to cross-react with bovine, canine, feline, and rat smooth muscle myosin heavy chains.