missing translation for 'onlineSavingsMsg'
Learn More

Myogenin Mouse, Alexa Fluor 488, Clone: F5D, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-5643-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15312040

  • £80.62 / 25µg


Estimated Shipment date
from Supplier 31-07-2017
Add to basket

Disclaimers:

For Research Use Only.


Specifications

Description

This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predominantly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control.
Description & Specifications

Specifications

Myogenin
F5D
Alexa Fluor 488
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG1
RUO
Primary
Rat
Immunocytochemistry
0.5mg/mL
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal