Myogenin Mouse, Alexa Fluor 488, Clone: F5D, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-5643-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg

Disclaimers: For Research Use Only.

Product Code. 15312040

Quantity Price
1 £ 80.62 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification


Format Conjugated
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Species Reactivity Canine, Human, Mouse, Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone F5D
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Conjugate Alexa Fluor 488
Antigen Myogenin
Isotype IgG1
Regulatory Status RUO
Applications Immunocytochemistry

This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predominantly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control.