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Myogenin Monoclonal Antibody (F5D), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£192.00 - £405.00

Specifications

Antigen Myogenin
Clone F5D
Concentration 0.5 mg/mL
Applications Immunocytochemistry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15312040
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Affymetrix eBioscience
53-5643-80
25 μg
£192.00
25µg
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Estimated Shipment: 07-05-2024
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15322040
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Affymetrix eBioscience
53-5643-82
100 μg
£405.00
100µg
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Estimated Shipment: 07-05-2024
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Description

Description

Description: This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34-kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predominantly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control. Applications Reported: This F5D antibody has been reported for use in immunocytochemistry. Applications Tested: This F5D antibody has been tested by immunocytochemistry of the C2C12 cell line. This can be used at less than or equal to 5-20 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Myogenin Monoclonal antibody specifically detects Myogenin in Canine, Human, Mouse, Rat samples. It is validated for Immunocytochemistry.
Specifications

Specifications

Myogenin
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
bHLHc3; Class C basic helix-loop-helix protein 3; MYF4; Myf-4; myo; MYOD1-related protein; MYOG; Myogenic factor 4; Myogenic factor-4; myogenin; myogenin (myogenic factor 4)
MYOG
Primary
4° C, store in dark, DO NOT FREEZE!
MYOG
F5D
Immunocytochemistry
Alexa Fluor 488
Mouse
Canine, Human, Mouse, Rat
P12979, P15173, P20428
17928, 29148, 4656, 490224
IgG1
Affinity chromatography
Antibody
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