Myeloperoxidase (MPO) Mouse anti-Human, PE, Clone: MPO455-8E6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1299-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15516876

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 28-04-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Format Conjugated
Isotype IgG1
Quantity 25 tests
Primary or Secondary Primary
Applications Flow Cytometry (Intracellular Staining)
Monoclonal or Polyclonal Monoclonal
Conjugate PE
Species Reactivity Human
Host Species Mouse
Antigen Myeloperoxidase (MPO)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone MPO455-8E6
Concentration 5μL (0.5μg)/test

The monoclonal antibody MPO455-8E6 recognizes myeloperoxidase (MPO), a protein within the azurophilic granules of myeloid cells. MPO is a multimeric protein comprised of two 55kDa subunits and two 15kDa subunits. The larger subunits associate with a heme protein resulting in a greenish color. As an enzyme, MPO breaks down hydrogen peroxide and oxidizes tyrosine. The products of this reaction, hypochlorous acid and tyrosyl radical, cause the cytotoxic and killing effects characteristic of neutrophils. Myeloperoxidase is important in the diagnosis of some cancers and increases in serum levels have been shown to correlate with cardiac events.