Myeloperoxidase (MPO) Mouse anti-Human, FITC, Clone: MPO455-8E6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-1299-42

Product Code. 15586486

Disclaimers:

For Research Use Only.

Description

The monoclonal antibody MPO455-8E6 recognizes myeloperoxidase (MPO), a protein within the azurophilic granules of myeloid cells. MPO is a multimeric protein comprised of two 55kDa subunits and two 15kDa subunits. The larger subunits associate with a heme protein resulting in a greenish color. As an enzyme, MPO breaks down hydrogen peroxide and oxidizes tyrosine. The products of this reaction, hypochlorous acid and tyrosyl radical, cause the cytotoxic and killing effects characteristic of neutrophils. Myeloperoxidase is important in the diagnosis of some cancers and increases in serum levels have been shown to correlate with cardiac events.

Specifications

• Antigen: Myeloperoxidase (MPO)
• Clone: MPO455-8E6
• Conjugate: FITC
• Format: Conjugated
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Flow Cytometry (Intracellular Staining)
• Concentration: 5μL (0.5μg)/test
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Murine
• Quantity: 100 Tests
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal