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Musashi-1 Rat, Clone: 14H1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9896-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15248217

  • £60.53 / 25µg


Estimated Shipment
02-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 14H1 monoclonal antibody recognizes human Musashi-1 (MSI-1), a 39kDa RNA binding protein. Musashi-1 is expressed in CNS stem and progenitor cells with decreased expression in differentiating cells. Musashi-1 functions as a translational repressor, directly regulating its target proteins, Numb and p21 (CIP1). Musashi-1 has been shown to be expressed in stem cells in a variety of other tissues such as the gut, stomach, mammary gland, and hair follicles. In addition to normal tissue expression, Musashi-1 expression has been identified in cells from several tumor types, mainly pulmonary and adenocarcinoma, as well as large and small cell carcinomas. Recently, expression of Musashi-1 in ischemic lesions following stroke provides evidence for neurogenesis as well as the role of Musashi-1 in regulating apoptosis.

Musashi-1 is highly conserved and the 14H1 antibody also recognizes mouse and rat Musashi-1.
Description & Specifications

Specifications

Musashi-1
14H1
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG2a
RUO
Primary
Rat
Western Blot
0.5mg/mL
Purified
Rat
25μg
Store at 2-8°C. Avoid repeated freeze/thaw cycles.
Monoclonal