MULT1 (NKG2D Ligand) Armenian Hamster anti-Mouse, Rat, Clone: 5D10, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-5863-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15217527

Quantity Price
1 £ 48.31 / 50µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Conjugate Unlabeled
Antigen MULT1 (NKG2D Ligand)
Primary or Secondary Primary
Format Purified
Isotype IgG
Storage Requirements Store at 2-8°C.
Quantity 50μg
Gene Alias NKG2DL, MULT-1
Species Reactivity Mouse, Rat
Clone 5D10
Concentration 0.5mg/mL
Host Species Armenian Hamster
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The 5D10 monoclonal antibody reacts with the murine MULT-1 (Murine ULBP-Like Transcript 1). MULT-1 is a type I transmembrane protein with two Ig-like domain and is one of the known murine NKG2-D ligands that include RAE1 molecules (alpha, beta, epsilon, gamma and delta) and H60. MULT-1 is a high affinity ligand for NKG2D.Expression of NKG2-D ligands is low or absent on normal adult tissues. However, stressed or transformed cells express NKG2-D ligand and can activate NK cell tumoricidal activity. Until now, the expression of NKG2-D ligands has been mainly studied with NKG2-D tetramers recognizing all NKG2-D ligands.