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Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Brand:  Tocris Bioscience™ 1212/10

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13438893

  • £133.65 / 10mg

Estimated Shipment
27-06-2019

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Description

Description

Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. Also available as part of the Group I mGlu Receptor Tocriset™ .
Specifications

Specifications

2-Methyl-6-(phenylethynyl)pyridine hydrochloride
>99%
Observed MW: 229.71
Soluble to 100mM in DMSO
219911-35-0
C14H11N.HCl
10mg
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