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Tocris Bioscience™ MPEP hydrochloride
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
POA
Specifications
| Assay Percent Range | >99% |
|---|---|
| Chemical Name or Material | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| CAS | 219911-35-0 |
Description
Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.Specifications
| >99% | |
| 2-Methyl-6-(phenylethynyl)pyridine hydrochloride | |
| 219911-35-0 |
For Research Use Only