missing translation for 'onlineSavingsMsg'
Learn More

eBioscience™ Annexin V, FITC, Recombinant Protein

Recombinant Protein

Brand:  Affymetrix eBioscience BMS306FI-20

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15531917

  • £64.86 / 20 tests


EU Stock 3
Add to basket

Specifications

Description

Annexins are a family of calcium-dependent phospholipid-binding proteins, which bindto phosphatidylserine (PS) to identify apoptotic cells. In healthy cells, PS is predominantlylocated along the cytosolic side of the plasma membrane. Upon initiation of apoptosis,PS loses its asymmetric distribution in the phospholipid bilayer and translocates tothe extracellular membrane, which is detectable with fluorescently labeled AnnexinV. In early stages of apoptosis, the plasma membrane excludes viability dyes such aspropidium iodide (PI) and 7-AAD, therefore cells which display only Annexin V staining(PI/7-AAD negative) are in early stages of apoptosis. During late-stage apoptosis, loss ofcell membrane integrity allows Annexin V binding to cytosolic PS, as well as cell uptakeof PI and 7-AAD. Annexin V staining, paired with 7-AAD or PI is widely used to identifyapoptotic stages by flow cytometry.
Description & Specifications

Specifications

Flow Cytometric Analysis
35.8kDa
SDS-gel electrophoresis and reverse phase HPLC
20 tests
Annexin V-FITC is stable at 2-8deg;C as indicated on the label. Do not freeze!
E. Coli
Annexin V exhibits anti-phospholipase activity and binds to phosphatidylserine (PS).
FITC
Solution containing 50mM TRIS, 100mM NaCl, 1% BSA, 0.02% Sodium Azide, pH 7.4
Annexin V
>89%
E. coli
RUO
Lipocortin V, Endonexin II, Calphobindin I
Recombinant Protein
Yes