eBioscience™ Human CXCL10 (IP-10), Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand: eBioscience™

Manufacturer Part Number: 34-8967-82

100UG Human CXCL10 (IP-10) Recombinant Protein Carrier-Free

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Product Code. 15588836


This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Description and Specification


Accession Number NM_001565
Molecular Weight 8.8kDa
Name CXCL10 (IP-10)
Purification Method SDS-PAGE
Purity >97%
Quantity 100μg
Recombinant Yes
Source E. coli
Storage Requirements Store at less than or equal to -70°C.
Regulatory Status RUO
Structural Form E. coli-expressed amino acids Val22-Pro98, accession number NM_001565
Concentration 0.5mg/mL
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Gene Symbol Interferon Inducible Protein 10
Conjugate Unlabeled
Biological Activity The bioactivity of this protein was determined by transmigration assay of human T lymphocytes, with maximum chemotaxis observed at 100-200ng/mL.
Product Type Recombinant Protein, Carrier-Free
Cross Reactivity Human
For Use With (Application) Cytokine Bioassays
Formulation Sterile liquid; phosphate-buffered saline, pH 7.2

CXCL10, also known as IP-10 (Interferon Inducible Protein-10), is a member of the CXC family of chemokines. It is secreted by monocytes, epithelial cells, and endothelial cells in response to IFN gamma or other pro-inflammatory cytokines and stimuli. CXCL10 signaling is mediated by the g protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. In addition to its role as a chemoattractant, CXCL10 is also a potent inhibitor of angiogenesis and exhibits antitumor activity.