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eBioscience™ Human GM-CSF, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand:  Affymetrix eBioscience 34-8339-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15588786

  • £1154.96 / 500µg


Estimated Shipment date
from Supplier 03-07-2017
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Specifications

Description

Human GM-CSF (Granulocyte/Monocyte-Colony Stimulating Factor) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF alpha, IL-1, IL-2 and IFN gamma. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their progenitors.
Description & Specifications

Specifications

NM_000758
Sterile liquid; 10mM sodium phosphate, pH 7.2, 150mM NaCl. 0.22μm filtered.
GM-CSF
≥95%
E. coli
RUO
Less than 0.01ng/μg cytokine as determined by the LAL assay.
The ED50 of this protein, as measured by TF-1 cell proliferation assay, is less than or equal to 100pg/mL. This corresponds to a specific activity of greater than or equal to 1 x 107 Units/mg.
Unlabeled
Yes
Cytokine Bioassays
The protein is not methionylated at the N-terminal and has a predicted molecular mass of 14,478. The DTT reduced protein migrates as a 14kDa polypeptide on SDS-PAGE. The non-reduced protein migrates as a 13kDa polypeptide.
SDS-PAGE
500μg
Store at less than or equal to -70°C.
E. coli expressed amino acids ala 18 - glu144 of mature human GMCSF accession # NM_000758
Granulocyte/Macrophage-Colony Stimulating Factor
Recombinant Protein, Carrier-Free
Human