eBioscience™ Mouse IL-6, Recombinant Protein

Mouse Recombinant Protein

Brand: eBioscience™

Manufacturer Part Number: 14-8061-62

Recombinant Mouse IL-6(Interleukin-6, IL6) 5 ug

UNSPSC: 12000000

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 12730060

Quantity Price
1 £185.40 / Each
Estimated Shipment date
from Supplier 31-10-2016
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Description and Specification


Accession Number MMINTL6
Conjugate Unlabeled
Cross Reactivity Mouse
For Use With (Application) Cytokine Bioassays, ELISA
Formulation Sterile liquid: 0.1M glycine, pH 3.0, 0.5% BSA. 0.22μm filtered.
Molecular Weight The protein is methionylated at the N-terminal. The DTT reduced and non-reduced protein migrate as 19kDa polypeptides on SDS-PAGE.
Name IL-6
Purification Method SDS-PAGE
Purity >98%
Quantity 5μg
Recombinant Yes
Source E. coli
Regulatory Status RUO
Structural Form E. coli expressed amino acids Phe 25-Thre 211 of mature mouse IL-6 accession # MMINTL6
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Gene Symbol Interleukin-6, IL6
Validated Application ELISA, FA
Biological Activity The ED50 of this protein, as measured by B9 cell proliferation assay, is less than or equal to 5pg/mL. This corresponds to a specific activity of greater than or equal to 2 x 108 Units/mg.

Mouse IL-6 (also known as B Cell Stimulating Factor, BCSF, and BSF-2) is a ∽21-28 kDa factor produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences the antigen-specific immune response, inflammatory response, and the development of neurons, and is a major mediator of the acute phase reaction.