eBioscience™ Mouse IL-6, Recombinant Protein

Mouse Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8061-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15577486

Quantity Price
1 £ 317.33 / 25µg
EU Stock 7
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Description and Specification

Specification

Gene Symbol Interleukin-6, IL6
Recombinant Yes
Cross Reactivity Mouse
Structural Form E. coli expressed amino acids Phe 25-Thre 211 of mature mouse IL-6 accession # MMINTL6
Regulatory Status RUO
Conjugate Unlabeled
Formulation Sterile liquid: 0.1M glycine, pH 3.0, 0.5% BSA. 0.22μm filtered.
Molecular Weight The protein is methionylated at the N-terminal. The DTT reduced and non-reduced protein migrate as 19kDa polypeptides on SDS-PAGE.
Product Type Recombinant Protein
Quantity 25μg
Name IL-6
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
For Use With (Application) Cytokine Bioassays , ELISA
Storage Requirements Store at less than or equal to -70°C.
Source E. coli
Purity >98%
Biological Activity The ED50 of this protein, as measured by B9 cell proliferation assay, is less than or equal to 5pg/mL. This corresponds to a specific activity of greater than or equal to 2 x 108 Units/mg.
Accession Number MMINTL6
Purification Method SDS-PAGE

Mouse IL-6 (also known as B Cell Stimulating Factor, BCSF, and BSF-2) is a ∽21-28 kDa factor produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences the antigen-specific immune response, inflammatory response, and the development of neurons, and is a major mediator of the acute phase reaction.