eBioscience™ Mouse GM-CSF, Recombinant Protein, Carrier-Free

Mouse Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 34-8331-85

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15548786

Quantity Price
1 £ 1154.96 / 500µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Cross Reactivity Mouse
Source E. coli
Accession Number NM_009969
Product Type Recombinant Protein, Carrier-Free
Gene Symbol Granulocyte/Macrophage-Colony Stimulating Factor
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Storage Requirements Store at less than or equal to -70°C.
Concentration 0.5mg/mL
Quantity 500μg
Structural Form E. coli expressed mature mouse GM-CSF accession # NM_009969
Biological Activity The ED50 of this protein, as measured by MC/9 cell proliferation assay, is less than or equal to 650pg/mL. This corresponds to a specific activity of greater than or equal to 1.5 x 106 Units/mg.
Molecular Weight 14kDa
Purity >98%
Regulatory Status RUO
Conjugate Unlabeled
For Use With (Application) Cytokine Bioassays
Formulation Sterile liquid; phosphate buffered saline, pH 7.2, 0.22μm filtered.
Purification Method SDS-PAGE
Recombinant Yes
Name GM-CSF

Mouse Granulocyte/Macrophage Colony Stimulating Factor (GM-CSF) is an ∽14 kDa factor produced mainly by activated T cells and macrophages. Other cell types, such as endothelium and fibroblasts, also secrete GM-CSF in response to TNF alpha, IL-2, IL-1, and IFN gamma. GM-CSF stimulates growth of macrophages, granulocytes and dendritic cells. GM-CSF is found as a membrane-bound form and also as a complex associated with the extracellular matrix. Non-glycosylated GM-CSF is biologically active.