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eBioscience™ Human BMP-2, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand:  Affymetrix eBioscience 34-8507-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15558806

  • £433.49 / 100µg


Estimated Shipment date
from Supplier 27-06-2017
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Specifications

Description

BMP-2 is one of fifteen bone morphogenetic proteins (BMP) belonging to the TGF-β superfamily. The BMPs were first identified as the active factors in demineralized bone matrix, with transcripts later being discovered in many other types of tissue. They are synthesized as large precursor molecules that must be cleaved into their active form and dimerize in order to exhibit functional activity. These dimers may include two identical or distinct BMP chains. BMP responsiveness appears to be limited to multipotent and immature cells. The BMPs are essential for osteogenesis and organogenesis during embryonic development, and also play a role in fracture and wound healing in adults.
Description & Specifications

Specifications

NP_001191
Cytokine Bioassays
13kDa
SDS-PAGE
100μg
Store at less than or equal to -70°C.
E. coli expressed amino acids Gln283-Arg396 accession number NP_001191
Bone Morphogenetic Protein 2
Recombinant Protein, Carrier-Free
Human
0.5mg/mL
Sterile liquid: 0.1M glycine, pH 3.0
BMP-2
>97%
E. coli
RUO
Less than 0.01ng/μg cytokine as determined by the LAL assay.
The ED50 of this protein, as determined by alkaline phosphatase induction in C3H/10T1/2 cells, is 0.25-1μg/mL. This corresponds to a specific activity of 4x103 - 1x103 Units/mg.
Unlabeled
Yes