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eBioscience™ Human Activin A, Recombinant Protein

Human Recombinant Protein

Brand:  Affymetrix eBioscience 14-8993-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15597556

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance



Activin A is a member of the TGF-β superfamily, along with the other activin proteins and the structurally related inhibins. The activins are dimeric proteins formed by the association of two of the four existing β subunits, βA, βB, βC, and βE. These subunits are shared with the inhibin proteins, which are heterodimers of one β and one α chain. Activin A is a homodimer of two 13 kDa βA subunits, which can also associate with βB or βC to form Activin AB or AC, respectively. Activin A is expressed by various cell types and exhibits pleiotropic effects including the regulation of metabolism, homeostasis, cell proliferation and differentiation, apoptosis, and tissue healing. Activin A has been recently reported to work in synergy with TGF-β to promote the induction of antigen specific iTreg cells leading to inhibition of Th1 and Th2-mediated responses.


Cytokine Bioassays
Store at less than or equal to -70°C.
Insect expressed amino acids Gly311-Ser426, accession number NM_002192
The ED50 of this protein, as measured by inhibition of MPC-11 mouse plasmacytoma cell proliferation, is 0.75-3ng/mL. This corresponds to a specific activity of 1.3 x 106 - 3.3 x 105 Units/mg.
Sterile liquid; 20mM glycine, 150mM NaCl with 1% BSA, pH 3.0. 0.22μm filtered.
Activin A
Insect Cells
Less than 0.01ng/μg cytokine as determined by the LAL assay.
Recombinant Protein