eBioscience™ Human M-CSF, Recombinant Protein

Human Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8789-80

UNSPSC: 12000000

Code: NEW

Additional Details:
Additional Details: Weight: 1.00000kg



Product Code. 15149186

Quantity Price
1 £ 115.56 / 25µg
EU Stock 93
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Description and Specification

Specification

Regulatory Status RUO
Purification Method SDS-PAGE
Structural Form Human M-CSF Glu34-Ser190 accession # NM-172211 expressed in insect cells with a C-terminal 6X His tag.
Gene Symbol Macrophage colony stimulating factor, monocyte colony stimulating factor
Purity >98%
Cross Reactivity Human
Recombinant Yes
Source Insect Cells
Conjugate Unlabeled
Storage Requirements Store at less than or equal to -70°C.
Name M-CSF
Product Type Recombinant Protein
Biological Activity The bioactivity of this protein, as determined in a cell proliferation assay on M-NFS-60 cells, is 3ng/mL. This corresponds to a specific activity of 3.3 X 105 Units/mg.
Quantity 25μg
Formulation Sterile liquid; phosphate-buffered saline 1% BSA, 0.22μm filtered.
Molecular Weight 36kDa
Accession Number NM-172211
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
For Use With (Application) Cytokine Bioassays

Human Macrophage Colony Stimulating Factor (M-CSF, also called CSF-1) is a ∽36 kDa disulfide-linked homodimer produced by a variety of cells including fibroblasts, macrophages, bone marrow stromal cells and endothelial cells. M-CSF regulates macrophage survival, proliferation and differentiation. M-CSF also enhances macrophage killing of tumor cells and microorganisms and regulates cytokine production from macrophages.