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eBioscience™ Human Glial Cell Derived Neurotrophic Factor (GDNF), Recombinant Protein

Human Recombinant Protein

Brand:  Affymetrix eBioscience 14-8506-62

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15587536

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Description

Description

Glial Cell derived Neurotrophic Factor (GDNF), a member of the TGFß superfamily, is a neurotrophic factor that promotes the survival of various neuronal populations in both the central and peripheral nervous systems during their development. Neuronal subpopulations affected by GDNF include motor neurons, midbrain dopaminergic neurons and Purkinje cells. GDNF is conserved across mammalian species with human and rat orthologs sharing approximately 93% amino acid sequence identity. E. coli-produced recombinant human GDNF is a disulfide-linked, non-glycosylated homodimer composed of two 135 amino acid polypeptides.
Specifications

Specifications

Cytokine Bioassays
30kDa (homodimer)
SDS-PAGE
5μg
Store at less than or equal to -70°C.
E. coli expressed amino acids Ser78 - Ile211 Accession # CAG46721
The ED50 , calculated by dose-dependent induction of rat C6 cell proliferation, is 1ug/mL, corresponding to a specific activity of 1x103 units/mg.
Unlabeled
Yes
Sterile liquid; 10mM phosphate buffer, 150mM NaCl, 1.0% BSA. 0.22μm filtered.
Glial Cell Derived Neurotrophic Factor (GDNF)
>98%
E. coli
RUO
Less than 0.01ng/μg cytokine as determined by the LAL assay.
Recombinant Protein
Human