eBioscience™ Human IFN gamma, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Overview
Brand: eBioscience™

Manufacturer Part Number: 34-8319-85

500UG Human IFN gamma Recombinant Protein Carrier-Free

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15588776

Quantity Price
1 £ 539.4 / 500µg
Estimated Shipment date
from Supplier 14-12-2016
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Description and Specification

Specification

Accession Number NM_000619
Concentration 0.5mg/mL
Conjugate Unlabeled
Cross Reactivity Human
For Use With (Application) Cytokine Bioassays
Formulation Sterile liquid: 20mM phosphate, 400mM NaCl, pH 7.2, 0.22μm filtered.
Molecular Weight The methionylated N-terminal protein migrates as a 16kDa polypeptide on SDS-PAGE.
Name IFN gamma
Purification Method SDS-PAGE
Purity >98%
Quantity 500μg
Recombinant Yes
Source E. coli
Storage Requirements Store at less than or equal to -70°C.
Regulatory Status RUO
Structural Form E. coli expressed amino acids Gln 24-Gln 166 of mature human IFN gamma accession # NM_000619
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Gene Symbol Interferon-gamma
Biological Activity The ED50 of this protein, as measured by EMC virus protection assay using A549 cells, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 106 Units/mg.
Product Type Recombinant Protein, Carrier-Free

Human IFN gamma is an ∽20 kDa factor produced by activated T, B and NK cells and is an anti-viral and anti-parasitic cytokine. IFN gamma in synergy with other cytokines, such as TNF alpha, inhibits proliferation of normal and transformed cells. Immunomodulatory effects of IFN gamma are exerted on a wide range of cell types expressing the high affinity receptors for IFN-γ. Glycosylation of IFN gamma does not affect its biological activity.