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eBioscience™ Human IL-34, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand:  Affymetrix eBioscience 34-8684-61

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15528816

  • £60.53 / 2µg


Estimated Shipment date
from Supplier 02-08-2017
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Specifications

Description

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
Description & Specifications

Specifications

Functional Assays
52.5kDa
SDS-PAGE and HPLC
2μg
Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier protein (e.g., 0.1% BSA) at less than or equal to -20°C.
HEK 293 cells (amino acids Asn21-Pro242; Accession # NP_001166243); contains a C-terminal 8X His tag
The activity of this protein was determined by measuring MCP-1 secretion from normal human peripheral blood cells.
Unlabeled
Yes
Lyophilized from 20mM citric acid, pH 3.0
IL-34
>95%
HEK 293 cells
RUO
Less than 0.1ng/μg cytokine as determined by the LAL assay
Recombinant Protein, Carrier-Free
Human