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Invitrogen™ MCP-1/CCL2 Mouse Uncoated ELISA Kit with Plates

Uncoated ELISA Kit with Plates

£132.00 - £460.00

Specifications

For Use With (Application) ELISA
Synonym Monocyte chemotactic protein 1
Target Mouse
Sensitivity 15 pg/mL
Storage Requirements 2°C to 8°C
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Alert:

Contains Azide


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Product Code Brand Quantity Price Quantity & Availability  
15571137
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Invitrogen™
88-7391-76
20 x 96 Tests
£460.00
Pack of 20
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15581137
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Invitrogen™
88-7391-86
10 x 96 Tests
£330.00
Pack of 10
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15561137
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Invitrogen™
88-7391-22
2 x 96 Tests
£132.00
Pack of 2
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Estimated Shipment
26-02-2021
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Description

Description

MCP-1 (Monocyte chemotactic protein-1, CCL2) has a predicted molecular weight of approximately 11kDa, however, it may run at a higher molecular weight due to glycosylation. MCP-1 is a member of the cytokine family and plays an important role in immunoregulation and inflammatory processes. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. MCP-1 is linked with tumor progression, angiogenesis, and displays selective chemotactic activity towards monocytes and basophils but not neutrophils or eosinophils. MCP-1 is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. Further, MCP-1 is indicated in the etiology of several immune disorders, and is upregulated during infection and inflammation. While MCP-1 is a potent basophil activator, the related protein MCP-2 stimulates both eosinophils and basophils. MCP-3 has been shown to have the broadest range of influence. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.
Specifications

Specifications

ELISA
Mouse
2°C to 8°C
15-2,000 pg/mL
ELISA Kit
Mouse
HRP
Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL
24 hr. 30 min.
Monocyte chemotactic protein 1
15 pg/mL
P10148
Biotin
Supernatant
Colorimetric Microplate Reader
RUO
1 hr. 45 min.
SDS

For Research Use Only