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Invitrogen™ MCP-1/CCL2 Mouse Uncoated ELISA Kit with Plates
Uncoated ELISA Kit with Plates
£132.00 - £460.00
Specifications
For Use With (Application) | ELISA |
---|---|
Synonym | Monocyte chemotactic protein 1 |
Target | Mouse |
Sensitivity | 15 pg/mL |
Storage Requirements | 2°C to 8°C |
Alert:
Contains Azide
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15571137
|
Invitrogen™
88-7391-76 |
20 x 96 Tests |
£460.00
Pack of 20 |
|
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15581137
|
Invitrogen™
88-7391-86 |
10 x 96 Tests |
£330.00
Pack of 10 |
|
|||||
15561137
|
Invitrogen™
88-7391-22 |
2 x 96 Tests |
£132.00
Pack of 2 |
26-02-2021 |
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Description
MCP-1 (Monocyte chemotactic protein-1, CCL2) has a predicted molecular weight of approximately 11kDa, however, it may run at a higher molecular weight due to glycosylation. MCP-1 is a member of the cytokine family and plays an important role in immunoregulation and inflammatory processes. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. MCP-1 is linked with tumor progression, angiogenesis, and displays selective chemotactic activity towards monocytes and basophils but not neutrophils or eosinophils. MCP-1 is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. Further, MCP-1 is indicated in the etiology of several immune disorders, and is upregulated during infection and inflammation. While MCP-1 is a potent basophil activator, the related protein MCP-2 stimulates both eosinophils and basophils. MCP-3 has been shown to have the broadest range of influence. MCP-1 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.Specifications
ELISA | |
Mouse | |
2°C to 8°C | |
15-2,000 pg/mL | |
ELISA Kit | |
Mouse | |
HRP | |
Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL | |
24 hr. 30 min. |
Monocyte chemotactic protein 1 | |
15 pg/mL | |
P10148 | |
Biotin | |
Supernatant | |
Colorimetric Microplate Reader | |
RUO | |
1 hr. 45 min. |
For Research Use Only