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Monastrol, Tocris Bioscience™

Selective inhibitor of mitotic kinesin Eg5

Brand:  Tocris (Bio-Techne) 1305/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13469093

  • £188.16 / 10mg

Estimated Shipment date
from Supplier 25-03-2020

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Description

Description

Potent, cell-permeable, small molecule mitosis inhibitor that does not interact with tubulin. Arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC50 = 14 μM).
Specifications

Chemical Identifiers

254753-54-3
292.353
monastrol, ethyl 4-3-hydroxyphenyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, 4-3-hydroxyphenyl-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4h-pyrimidin-5-carboxylic acid ethyl ester, d0zk2g, monastrol hplc , solid, inverted exclamation marka-monastrol, 6-methyl-4-3-hydroxyphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-4-methyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-4-methyl-2-thioxo-1,3,6-trihydropyrimidine-5-carboxy late
CHEBI:75382
CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
C14H16N2O3S
LOBCDGHHHHGHFA-UHFFFAOYSA-N
2987927
ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

Specifications

10mg
254753-54-3
monastrol, ethyl 4-3-hydroxyphenyl-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, 4-3-hydroxyphenyl-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4h-pyrimidin-5-carboxylic acid ethyl ester, d0zk2g, monastrol hplc , solid, inverted exclamation marka-monastrol, 6-methyl-4-3-hydroxyphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-4-methyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate, ethyl 6-3-hydroxyphenyl-4-methyl-2-thioxo-1,3,6-trihydropyrimidine-5-carboxy late
CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
292.353
CHEBI:75382
>98%
Monastrol
C14H16N2O3S
LOBCDGHHHHGHFA-UHFFFAOYSA-N
ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate
2987927
292.35
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