Molecular Probes™ FM 1-43 Dye (N-(3-Triethylammoniumpropyl)-4-(4-(Dibutylamino) Styryl) Pyridinium Dibromide)

Membrane probe

Overview
Brand: Invitrogen

Manufacturer Part Number: T3163

N-(3-TRIETHYLAMMONIUMPROPFM 1-43 membrane probe is an excellent reagent

UNSPSC: 12161500

Code: 50

Additional Details:
Additional Details: Weight: 0.00525kg



Product Code. 10769623

Quantity Price
1 £ 360.0 / 1mg
EU Stock 2
Add to basket

For Research Use Only. All usage must comply with product instructions.
 

Description and Specification

Specification

Quantity 1mg
Target Plasma Membrane
For Use With (Equipment) Fluorescence Microscope
Detection Method Fluorescent
Color Orange

FM 1-43 is an excellent reagent both for identifying actively firing neurons and for investigating the mechanisms of activity-dependent vesicle cycling. This water-soluble dye, which is nontoxic to cells and virtually nonfluorescent in aqueous medium, is believed to insert into the outer leaflet of the cell membrane where it becomes intensely fluorescent. In a neuron that is actively releasing neurotransmitters, the dye becomes internalized within the recycled synaptic vesicles and the nerve terminals become brightly stained. The nonspecific staining of cell-surface membranes can simply be washed off prior to viewing.

FM 1-43 membrane probe is also available as 1mg packaged into 10 vials, each containing 100μg (T-35356). FM 1-43FX membrane probe (F-35355), an analog of FM 1-43 membrane probe that can be fixed in place using aldehyde-based fixatives, is also available.

Cell Analysis, Cell Tracing & Tracking, Cell Viability, Proliferation & Function, Endocytosis, Exocytosis & Phagocytosis, General Cell Tracing, Neuronal Tracing