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ML 130, Tocris Bioscience™

Inhibits NOD1-induced NF-κB activation

Brand:  RD Systems (Bio-Techne) 4354/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13434614

  • £189.63 / 10mg

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Description

Description

Potent and selective inhibitor of NOD1; displays 36-fold selectivity for NOD1 over NOD2 (IC50 values are 0.56 and >20 μM for NOD1 and NOD2 respectively). Inhibits NOD1-induced NF-κB activation in HEK293 cells with no cytotoxicity. Shown to alter subcellular targeting of NOD1; also thought to alter the conformation of NOD1 protein in vitro.
Specifications

Chemical Identifiers

799264-47-4
287.337
nodinitib-1, noditinib-1, 1-4-methylphenyl sulfonylbenzimidazol-2-amine, 1-toluene-4-sulfonyl-1h-benzoimidazol-2-ylamine, 1-4-methylphenyl sulfonyl-1h-benzimidazol-2-amine, 1-4-methylbenzenesulfonyl-1,3-benzodiazol-2-amine, noditinibeta-1, nodithinib 1, ml130 nodinitib-1, 1-tosylbenzimidazol-2-yl amine
1-(4-methylphenyl)sulfonylbenzimidazol-2-amine
C14H13N3O2S
SRFABRWQVPCPRG-UHFFFAOYSA-N
1088438
CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N

Specifications

10mg
799264-47-4
nodinitib-1, noditinib-1, 1-4-methylphenyl sulfonylbenzimidazol-2-amine, 1-toluene-4-sulfonyl-1h-benzoimidazol-2-ylamine, 1-4-methylphenyl sulfonyl-1h-benzimidazol-2-amine, 1-4-methylbenzenesulfonyl-1,3-benzodiazol-2-amine, noditinibeta-1, nodithinib 1, ml130 nodinitib-1, 1-tosylbenzimidazol-2-yl amine
CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N
287.337
287.34
ML 130
C14H13N3O2S
SRFABRWQVPCPRG-UHFFFAOYSA-N
1-(4-methylphenyl)sulfonylbenzimidazol-2-amine
1088438
>99%
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