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MK 886, Tocris Bioscience™

Inhibitor of 5-lipoxygenase-activating protein (FLAP). Restrictions apply. See special conditions on product page.

Brand:  Tocris (Bio-Techne) 131110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459113

  • £173.00 / 10mg


Estimated Shipment
29-06-2018
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Description

Description

An inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Acts by inhibiting 5-lipoxygenase-activating protein (FLAP) (IC50 = 30 nM for inhibition of [125I]-L-691,678 photoaffinity labelling). Also moderately potent PPARα antagonist (IC50 = 0.5-1 μM). Orally active in vivo.
Specifications

Chemical Identifiers

Solid

Specifications

MK 886
118414-82-7
Solid
472.08
10mg
>98%
C27H34ClNO2S
1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-Glc alpha,Glc alpha-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid
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