missing translation for 'onlineSavingsMsg'
Learn More

MK 0343, Tocris Bioscience™

Subtype-selective GABAA receptor partial agonist

Brand:  RD Systems (Bio-Techne) 4415/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

 View more versions of this product

Product Code. 13464714

  • £805.08 / 50mg


Estimated Shipment
03-09-2018
Add to basket

Description

Description

Subtype-selective GABAA partial agonist (Ki values are 0.21, 0.22, 0.23 and 0.40 for α3, α1, α5 and α2 respectively); occupies the benzodiazepine site of GABAA receptors. Displays greater agonist efficacy at α3 compared to α1. Exhibits anxiolytic and non-sedating properties in rodent models. Brain penetrant.
Specifications

Chemical Identifiers

233275-76-8
397.39
7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazo[4,3-b]pyridazine
C19H17F2N7O
GOIFCXRIFSYPFG-UHFFFAOYSA-N
22609888

Specifications

MK 0343
233275-76-8
C19H17F2N7O
GOIFCXRIFSYPFG-UHFFFAOYSA-N
7-cyclobutyl-3-(2,6-difluorophenyl)-6-[(2-methyl-1,2,4-triazol-3-yl)methoxy]-[1,2,4]triazolo[4,3-b]pyridazine
22609888
50mg
>99%
7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazo[4,3-b]pyridazine
CN1C(=NC=N1)COC2=NN3C(=NN=C3C4=C(C=CC=C4F)F)C=C2C5CCC5
397.39
397.38
Videos