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MK 0343, Tocris Bioscience™

Subtype-selective GABAA receptor partial agonist

Brand:  RD Systems (Bio-Techne) 4415/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13464714

  • £840.00 / 50mg


Estimated Shipment
28-06-2018
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Description

Description

Subtype-selective GABAA partial agonist (Ki values are 0.21, 0.22, 0.23 and 0.40 for α3, α1, α5 and α2 respectively); occupies the benzodiazepine site of GABAA receptors. Displays greater agonist efficacy at α3 compared to α1. Exhibits anxiolytic and non-sedating properties in rodent models. Brain penetrant.
Specifications

Chemical Identifiers

MK 0343
C19H17F2N7O
397.38
7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazo[4,3-b]pyridazine

Specifications

MK 0343
233275-76-8
C19H17F2N7O
7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazo[4,3-b]pyridazine
50mg
>99%
397.38
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