MHC Class II Rat anti-Canine, APC, Clone: YKIX334.2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5909-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15578156

Quantity Price
1 £ 60.53 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Conjugate APC
Applications Flow Cytometry
Isotype IgG2a
Format Conjugated
Primary or Secondary Primary
Antigen MHC Class II
Clone YKIX334.2
Species Reactivity Canine
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Gene Alias MHC II
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 25 tests
Concentration 5μL (0.25μg)/test

This YKIX334.2 monoclonal antibody reacts with canine major histocompatibility complex (MHC) Class II. The MHC plays a significant role in immunity by presenting self and non-self antigens to T cells. In dogs, MHC Class II is expressed on all T and B cells, macrophages, fibroblasts, and kidney interstitial cells.

This monoclonal antibody has been reported to inhibit mixed lymphocyte reactions and T cell activation induced by MHC Class II antigen presentation in vitro. Also, YKIX334.2 recognition of MHC Class II is not allele-specific.