MHC Class II (I-A) Rat anti-Mouse, FITC, Clone: NIMR-4, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-5322-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15228239

Quantity Price
1 £ 98.97 / 100µg
EU Stock 1
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Description and Specification

Specification

Applications Flow Cytometry
Format Conjugated
Regulatory Status RUO
Primary or Secondary Primary
Gene Alias MHC II, IA
Clone NIMR-4
Conjugate FITC
Quantity 100μg
Concentration 0.5mg/mL
Isotype IgG2b
Host Species Rat
Species Reactivity Mouse
Antigen MHC Class II (I-A)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells. MHC Class II molecules are important for the selection of the TCR repertoire during the processes of positive and negative selection. MHC Class II expression is required for the positive selection of CD4+ T cells.