MHC Class II (I-A/I-E) Rat anti-Mouse, eVolve 655, Clone: M5/114.15.2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 86-5321-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15580837

Quantity Price
1 £ 167.38 / 100 tests
EU Stock 3
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Description and Specification

Specification

Quantity 100 tests
Clone M5/114.15.2
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This product should be used within 6 months from the date of receipt.
Applications Flow Cytometry
Format Conjugated
Isotype IgG2b
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Conjugate eVolve 655
Species Reactivity Mouse
Antigen MHC Class II (I-A/I-E)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL
Gene Alias MHC II, IA, IE, I-A/E, IA/IE
Regulatory Status RUO

The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.